Insl3 - insulin-like 3 Gene

Mus musculus

Also known as Rlf; Rlnl

Gene ID: 16336 | Gene type: protein coding

About Insl3

Summary

Predicted to enable G protein-coupled receptor binding activity and protease binding activity. Involved in regulation of male gonad development. Acts upstream of or within in utero embryonic development and male gonad development. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in extracellular space. Is expressed in cornea; ovary; testis; and trunk. Used to study cryptorchidism. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human INSL3 (Insulin like 3). [provided by Alliance of Genome Resources, Apr 2022]

Insl3 Products(1)

mRNA	Protein	Name
NM_013564.7	NP_038592.3	insulin-like 3 precursor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within in utero embryonic development	IMP IMP: Inferred from mutant phenotype	10319319	MGI
acts upstream of or within male gonad development	IMP IMP: Inferred from mutant phenotype	10319319	MGI
involved in regulation of male gonad development	IMP IMP: Inferred from mutant phenotype	10319319	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

insulin-like 3

Ley I-L	ley-I-L
leydig insulin-like peptide	relaxin-like factor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06840	INSL3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20428	Insl3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26937	Insl3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Insl3	NCBI	NCBI:3640

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