2. Gene
  3. Ica1 - islet cell autoantigen 1 Gene

Ica1 - islet cell autoantigen 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 69kDa; ICA69

Gene ID: 15893 | Gene type: protein coding

About Ica1

Summary

Predicted to enable membrane curvature sensor activity and protein domain specific binding activity. Predicted to be involved in regulation of protein-containing complex assembly and regulation of transport. Predicted to act upstream of or within neurotransmitter transport. Located in cytosol and synaptic vesicle membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and trigeminal nerve. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ICA1 (islet cell autoantigen 1). [provided by Alliance of Genome Resources, Apr 2022]

Ica1 Products(10)

mRNA Protein Name
NM_001252266.2 NP_001239195.1 islet cell autoantigen 1 isoform 2
NM_001410043.1 NP_001396972.1 islet cell autoantigen 1 isoform 1
NM_001410044.1 NP_001396973.1 islet cell autoantigen 1 isoform 1
NM_001410045.1 NP_001396974.1 islet cell autoantigen 1 isoform 2
NM_001410046.1 NP_001396975.1 islet cell autoantigen 1 isoform 2
NM_001410047.1 NP_001396976.1 islet cell autoantigen 1 isoform 3
NM_001410048.1 NP_001396977.1 islet cell autoantigen 1 isoform 4
NM_001410049.1 NP_001396978.1 islet cell autoantigen 1 isoform 5
NM_001410050.1 NP_001396979.1 islet cell autoantigen 1 isoform 6
NM_010492.4 NP_034622.3 islet cell autoantigen 1 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23630453 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
11029035 MGI
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
11029035 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

islet cell autoantigen 1

69 kDa islet cell autoantigen

ICAp69

islet cell autoantigen 1, 69 kDa

islet cell autoantigen p69

p69

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06511 ICA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17958 Ica1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24429 Ica1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ica1 NCBI NCBI:3382