Hey1 - hes-related family bHLH transcription factor with YRPW motif 1 Gene

Rattus norvegicus

Also known as Herp2

Gene ID: 155437 | Gene type: protein coding

About Hey1

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Involved in Notch signaling pathway and cellular response to glucocorticoid stimulus. Located in nucleus. Orthologous to human HEY1 (hes related family bHLH transcription factor with YRPW motif 1). [provided by Alliance of Genome Resources, Apr 2022]

Hey1 Products(1)

mRNA	Protein	Name
NM_001191845.2	NP_001178774.2	hairy/enhancer-of-split related with YRPW motif protein 1

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in Notch signaling pathway	IDA IDA: Inferred from direct assay	11741889	RGD
involved in cellular response to glucocorticoid stimulus	IEP IEP: Inferred from expression pattern	20666749	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

hairy/enhancer-of-split related with YRPW motif protein 1

hairy/enhancer-of-split related with YRPW motif 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0289	Lycorine hydrochloride	Inhibitor	99.89%	Unkown
HY-164410	MO-I-1100	Inhibitor	99.76%	Unkown
HY-RS06146	HEY1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19339	Hey1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25830	Hey1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hey1	NCBI	NCBI:23462

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