2. Gene
  3. Hoxb5 - homeobox B5 Gene

Hoxb5 - homeobox B5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hox-2.1

Gene ID: 15413 | Gene type: protein coding

About Hoxb5

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including embryonic skeletal system morphogenesis; endothelial cell differentiation; and regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; lung; and nervous system. Orthologous to human HOXB5 (homeobox B5). [provided by Alliance of Genome Resources, Apr 2022]

Hoxb5 Products(1)

mRNA Protein Name
NM_008268.2 NP_032294.2 homeobox protein Hox-B5
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
12897140 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12897140 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12897140 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12897140 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20211142 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
7828847 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
7828847 MGI
acts upstream of or within embryonic skeletal system development IGI
IGI: Inferred from genetic interaction
17626057 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
7828847 MGI
acts upstream of or within embryonic skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
7828847 MGI
acts upstream of or within endothelial cell differentiation IDA
IDA: Inferred from direct assay
12897140 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12897140 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12897140 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
1353982 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-B5

homeo box B5

homeobox protein H24.1

homeobox protein Hox-2.1

homeobox protein Mu-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06309 HOXB5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22559 Hoxb5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxb5 NCBI NCBI:3215