1. Gene
  2. Hoxb3 - homeobox B3 Gene

Hoxb3 - homeobox B3 Gene

Mus musculus

Also known as Hox-2.7

Gene ID: 15410 | Gene type: protein coding

About Hoxb3

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; face development; and nervous system development. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; gut; and skin. Orthologous to human HOXB3 (homeobox B3). [provided by Alliance of Genome Resources, Apr 2022]

Hoxb3 Products(2)

mRNA Protein Name
NM_001079869.1 NP_001073338.1 homeobox protein Hox-B3
NM_010458.2 NP_034588.2 homeobox protein Hox-B3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
21320481 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within cartilage development IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within definitive hemopoiesis IGI
IGI: Inferred from genetic interaction
17761289 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within embryonic skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
9441667 MGI
acts upstream of or within face development IDA
IDA: Inferred from direct assay
21320481 MGI
acts upstream of or within glossopharyngeal nerve morphogenesis IGI
IGI: Inferred from genetic interaction
9441667 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
24029230 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
21320481 MGI
acts upstream of or within regulation of neurogenesis IDA
IDA: Inferred from direct assay
21320481 MGI
acts upstream of or within rhombomere development IDA
IDA: Inferred from direct assay
21320481 MGI
acts upstream of or within thyroid gland development IGI
IGI: Inferred from genetic interaction
9520319 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-B3

homeo box B3

homeobox protein Hox-2.7

homeobox protein MH-23

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxb3 NCBI NCBI:3213