2. Gene
  3. Hoxa10 - homeobox A10 Gene

Hoxa10 - homeobox A10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hox-1.8; Hoxa-10

Gene ID: 15395 | Gene type: protein coding

About Hoxa10

Summary

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of a cluster on chromosome 6 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Hoxa10 Products(2)

mRNA Protein Name
NM_001122950.2 NP_001116422.1 homeobox protein Hox-A10 isoform b
NM_008263.3 NP_032289.2 homeobox protein Hox-A10 isoform a
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
12869760 MGI
acts upstream of or within embryonic limb morphogenesis IGI
IGI: Inferred from genetic interaction
12869760 MGI
acts upstream of or within male gonad development IGI
IGI: Inferred from genetic interaction
23760953 MGI
acts upstream of or within multicellular organism development IDA
IDA: Inferred from direct assay
11900456 MGI
acts upstream of or within proximal/distal pattern formation IGI
IGI: Inferred from genetic interaction
12869760 MGI
acts upstream of or within regulation of gene expression IGI
IGI: Inferred from genetic interaction
23760953 MGI
acts upstream of or within single fertilization IGI
IGI: Inferred from genetic interaction
23760953 MGI
acts upstream of or within skeletal system development IGI
IGI: Inferred from genetic interaction
12869760 MGI
acts upstream of or within spermatogenesis IGI
IGI: Inferred from genetic interaction
23760953 MGI
acts upstream of or within uterus development IGI
IGI: Inferred from genetic interaction
23760953 MGI
Cellular Component GO Annotation Evidence Reference Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
9343407 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-A10

homeo box A10

homeobox protein Hox-1.8

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06294 HOXA10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19259 Hoxa10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25748 Hoxa10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxa10 NCBI NCBI:3206