2. Gene
  3. Hnrnpk - heterogeneous nuclear ribonucleoprotein K Gene

Hnrnpk - heterogeneous nuclear ribonucleoprotein K Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as KBBP; NOVA; Hnrpk

Gene ID: 15387 | Gene type: protein coding

About Hnrnpk

Summary

The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including the nucleus, cytoplasm and mitochondria. This gene product is thought to interact with RNA, DNA, and protein, and is involved in multiple cellular processes, including transcription, chromatin remodeling, DNA damage response, signal transduction, mRNA splicing, export, and translation. Multiple transcript variants and protein isoforms exist, with some isoforms containing a unique C-terminus. There are four pseudogenes of this gene, found on chromosomes 2, 3, 7 and 13. [provided by RefSeq, Aug 2014]

Hnrnpk Products(22)

mRNA Protein Name
NM_001301340.1 NP_001288269.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301341.1 NP_001288270.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301343.1 NP_001288272.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301344.1 NP_001288273.1 heterogeneous nuclear ribonucleoprotein K isoform 3
NM_001301345.1 NP_001288274.1 heterogeneous nuclear ribonucleoprotein K isoform 4
NM_001360490.1 NP_001347419.1 heterogeneous nuclear ribonucleoprotein K isoform 2
NM_001360491.1 NP_001347420.1 heterogeneous nuclear ribonucleoprotein K isoform 5
NM_001360493.1 NP_001347422.1 heterogeneous nuclear ribonucleoprotein K isoform 6
NM_001360494.1 NP_001347423.1 heterogeneous nuclear ribonucleoprotein K isoform 3
NM_001360495.1 NP_001347424.1 heterogeneous nuclear ribonucleoprotein K isoform 4
NM_025279.3 NP_079555.1 heterogeneous nuclear ribonucleoprotein K isoform 2
NM_001301340.1 NP_001288269.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301341.1 NP_001288270.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301343.1 NP_001288272.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301344.1 NP_001288273.1 heterogeneous nuclear ribonucleoprotein K isoform 3
NM_001301345.1 NP_001288274.1 heterogeneous nuclear ribonucleoprotein K isoform 4
NM_001360490.1 NP_001347419.1 heterogeneous nuclear ribonucleoprotein K isoform 2
NM_001360491.1 NP_001347420.1 heterogeneous nuclear ribonucleoprotein K isoform 5
NM_001360493.1 NP_001347422.1 heterogeneous nuclear ribonucleoprotein K isoform 6
NM_001360494.1 NP_001347423.1 heterogeneous nuclear ribonucleoprotein K isoform 3
NM_001360495.1 NP_001347424.1 heterogeneous nuclear ribonucleoprotein K isoform 4
NM_025279.3 NP_079555.1 heterogeneous nuclear ribonucleoprotein K isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables RNA binding IDA
IDA: Inferred from direct assay
20548952 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9185665 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
23636947 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
24530304 MGI
acts upstream of or within regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
IMP: Inferred from mutant phenotype
20673990 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
27430620 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein K

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135691 hnRNPK-IN-1 ≥97.0% Unkown
HY-RS06273 HNRNPK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21137 Hnrnpk Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27655 Hnrnpk Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hnrnpk NCBI NCBI:3190