Grpr - gastrin releasing peptide receptor Gene

Mus musculus

Also known as GRP-R

Gene ID: 14829 | Gene type: protein coding

About Grpr

Summary

This gene encodes a multipass membrane protein that functions as a receptor for Gastrin releasing peptide. Signalling through this receptor is important in a variety of physiological processes, including responses to itching, satiety, and fear. [provided by RefSeq, May 2015]

Grpr Products(1)

mRNA	Protein	Name
NM_008177.3	NP_032203.1	gastrin-releasing peptide receptor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables G protein-coupled peptide receptor activity	IDA IDA: Inferred from direct assay	1671171	MGI
enables neuropeptide receptor activity	IMP IMP: Inferred from mutant phenotype	26658875	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	22000021	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in motor behavior	IMP IMP: Inferred from mutant phenotype	26658875	MGI
involved in phospholipase C-activating G protein-coupled receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	26658875	MGI
involved in positive regulation of behavioral fear response	IMP IMP: Inferred from mutant phenotype	34610277	MGI
involved in positive regulation of respiratory gaseous exchange	IMP IMP: Inferred from mutant phenotype	26855425	MGI
involved in psychomotor behavior	IMP IMP: Inferred from mutant phenotype	28280205	MGI
acts upstream of or within regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	11960700	MGI
involved in response to external biotic stimulus	IMP IMP: Inferred from mutant phenotype	28280205	MGI
involved in social behavior	IMP IMP: Inferred from mutant phenotype	28280205	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	1671171	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

gastrin-releasing peptide receptor

GRP-preferring bombesin receptor

Related Agents

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P0107	RC-3095	Antagonist	/	Phase 2
HY-P0039	BIM-26226	Antagonist	99.94%	Phase 1

Pre-clinical Phase

Bioactive Molecules (18)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-116216	PD 168368	Antagonist	≥99.0%	Unkown
HY-P0107A	RC-3095 TFA	Antagonist	98.92%	Unkown
HY-N2909	Aurantiamide	Inhibitor	99.27%	Unkown
HY-W782083	p-SCN-Bn-NOTA trihydrochloride		99.62%	Unkown
HY-P1423A	BA 1 TFA	Agonist	99.76%	Unkown
HY-P10896	NOTA-P2-RM26		97.20%	Unkown
HY-P5413	[Lys3]-Bombesin		/	Unkown
HY-W343750	[Tyr4]-Bombesin	Agonist	/	Unkown
HY-115974	GRPR antagonist-1		/	Unkown
HY-115975	GRPR antagonist-2	Antagonist	/	Unkown
HY-176150	AMTG-DA1	Ligand	/	Unkown
HY-P11352	JMV594	Antagonist	/	Unkown
HY-P1423	BA 1	Agonist	/	Unkown
HY-P5520	GB-6	Chemical	/	Unkown
HY-RS05847	GRPR Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-168633	PSMA/GRPR ligand 1		/	Unkown
HY-RS17163	Grpr Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23613	Grpr Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Grpr	NCBI	NCBI:2925

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