Grik3 - glutamate receptor, ionotropic, kainate 3 Gene

Mus musculus

Also known as GluK3; Glur7; Glur-7; GluR7-3; 9630027E11

Gene ID: 14807 | Gene type: protein coding

About Grik3

Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Transcript variants encoding different isoforms have been described for this gene, however, their full-length nature is not known. [provided by RefSeq, Jul 2008]

Grik3 Products(1)

mRNA	Protein	Name
NM_001081097.3	NP_001074566.1	glutamate receptor ionotropic, kainate 3 precursor

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables glutamate-gated calcium ion channel activity	IDA IDA: Inferred from direct assay	20007474	MGI
enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IDA IDA: Inferred from direct assay	17620617	MGI
enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IEP IEP: Inferred from expression pattern	17620617	MGI
enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IMP IMP: Inferred from mutant phenotype	17620617	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	15805114	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	17620617	MGI
is active in glutamatergic synapse	IEP IEP: Inferred from expression pattern	17620617	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	17620617	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	15805114	MGI
is active in postsynaptic density membrane	IDA IDA: Inferred from direct assay	26448475	MGI
is active in postsynaptic density membrane	IEP IEP: Inferred from expression pattern	26448475	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

glutamate receptor ionotropic, kainate 3

glutamate receptor 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05800	GRIK3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20947	Grik3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27464	Grik3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Grik3	NCBI	NCBI:2899

Name
Email *

	Sorry, but the email address you supplied was invalid.