Gpam - glycerol-3-phosphate acyltransferase, mitochondrial Gene

Mus musculus

Also known as P90; GPAT; GPAT1; GPAT-1

Gene ID: 14732 | Gene type: protein coding

About Gpam

Summary

Enables glycerol-3-phosphate O-acyltransferase activity. Acts upstream of or within several processes, including glycerolipid metabolic process; lipid homeostasis; and negative regulation of activation-induced cell death of T cells. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human GPAM (glycerol-3-phosphate Acyltransferase, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Gpam Products(3)

mRNA	Protein	Name
NM_001356285.2	NP_001343214.1	glycerol-3-phosphate acyltransferase 1, mitochondrial
NM_001410454.1	NP_001397383.1	glycerol-3-phosphate acyltransferase 1, mitochondrial
NM_008149.4	NP_032175.2	glycerol-3-phosphate acyltransferase 1, mitochondrial

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables glycerol-3-phosphate O-acyltransferase activity	IDA IDA: Inferred from direct assay	12417724	MGI
enables glycerol-3-phosphate O-acyltransferase activity	IMP IMP: Inferred from mutant phenotype	12417724	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of activated T cell proliferation	IMP IMP: Inferred from mutant phenotype	18971390	MGI
acts upstream of activation-induced cell death of T cells	IMP IMP: Inferred from mutant phenotype	18971390	MGI
acts upstream of or within acyl-CoA metabolic process	IMP IMP: Inferred from mutant phenotype	15878874	MGI
acts upstream of or within defense response to virus	IMP IMP: Inferred from mutant phenotype	19193813	MGI
acts upstream of or within fatty acid homeostasis	IMP IMP: Inferred from mutant phenotype	18522808	MGI
acts upstream of or within fatty acid metabolic process	IMP IMP: Inferred from mutant phenotype	12417724	MGI
acts upstream of or within glycerophospholipid metabolic process	IMP IMP: Inferred from mutant phenotype	18971390	MGI
acts upstream of or within interleukin-2 production	IMP IMP: Inferred from mutant phenotype	18971390	MGI
acts upstream of or within negative regulation of activation-induced cell death of T cells	IMP IMP: Inferred from mutant phenotype	18971390	MGI
acts upstream of or within phospholipid homeostasis	IMP IMP: Inferred from mutant phenotype	18522808	MGI
acts upstream of or within positive regulation of activated T cell proliferation	IMP IMP: Inferred from mutant phenotype	18971390	MGI
acts upstream of or within positive regulation of multicellular organism growth	IMP IMP: Inferred from mutant phenotype	12417724	MGI
acts upstream of or within regulation of cytokine production	IMP IMP: Inferred from mutant phenotype	18971390	MGI
acts upstream of or within response to glucose	IMP IMP: Inferred from mutant phenotype	15878874	MGI
involved in triglyceride biosynthetic process	IMP IMP: Inferred from mutant phenotype	12417724	MGI
acts upstream of or within triglyceride metabolic process	IMP IMP: Inferred from mutant phenotype	15878874	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in mitochondrial outer membrane	IMP IMP: Inferred from mutant phenotype	18339309	MGI
located in mitochondrion	IDA IDA: Inferred from direct assay	12417724	MGI
located in mitochondrion	IMP IMP: Inferred from mutant phenotype	18339309	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

glycerol-3-phosphate acyltransferase 1, mitochondrial

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05615	GPAM Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20747	Gpam Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27259	Gpam Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpam	NCBI	NCBI:57678

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