2. Gene
  3. Gp1ba - glycoprotein 1b, alpha polypeptide Gene

Gp1ba - glycoprotein 1b, alpha polypeptide Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as GPIba; GPIbalpha; GP-Ib alpha

Gene ID: 14723 | Gene type: protein coding

About Gp1ba

Summary

Acts upstream of or within blood coagulation and cell morphogenesis. Colocalizes with anchored component of external side of plasma membrane. Is expressed in dorsal root ganglion; embryo; liver; and spinal cord. Used to study Bernard-Soulier syndrome. Human ortholog(s) of this gene implicated in Bernard-Soulier syndrome; Bernard-Soulier syndrome type A2; myocardial infarction; non-arteritic anterior ischemic optic neuropathy; and platelet-type bleeding disorder 3. Orthologous to human GP1BA (glycoprotein Ib platelet subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Gp1ba Products(1)

mRNA Protein Name
NM_010326.3 NP_034456.2 platelet glycoprotein Ib alpha chain precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in blood coagulation IDA
IDA: Inferred from direct assay
18187573 MGI
acts upstream of or within blood coagulation IMP
IMP: Inferred from mutant phenotype
20650879 MGI
acts upstream of or within cell morphogenesis IMP
IMP: Inferred from mutant phenotype
10706630 MGI
acts upstream of or within hemostasis IMP
IMP: Inferred from mutant phenotype
10706630 MGI
involved in megakaryocyte development IMP
IMP: Inferred from mutant phenotype
18187573 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
28576878 MGI
colocalizes with external side of plasma membrane IDA
IDA: Inferred from direct assay
19443707 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet glycoprotein Ib alpha chain

glycoprotein Ibalpha

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05607 GP1BA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20029 Gp1ba Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26532 Gp1ba Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gp1ba NCBI NCBI:2811