2. Gene
  3. Gnai1 - guanine nucleotide binding protein (G protein), alpha inhibiting 1 Gene

Gnai1 - guanine nucleotide binding protein (G protein), alpha inhibiting 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hg1b; Gnai-1; Gialpha1

Gene ID: 14677 | Gene type: protein coding

About Gnai1

Summary

Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GTPase activating protein binding activity; and guanyl ribonucleotide binding activity. Predicted to be involved in several processes, including cellular response to forskolin; positive regulation of protein localization to cell cortex; and regulation of mitotic spindle organization. Predicted to act upstream of or within signal transduction. Predicted to be located in several cellular components, including centrosome; membrane raft; and midbody. Predicted to be part of heterotrimeric G-protein complex. Is expressed in several structures, including Grueneberg ganglion; forelimb; gonad; gut; and nervous system. Orthologous to human GNAI1 (G protein subunit alpha i1). [provided by Alliance of Genome Resources, Apr 2022]

Gnai1 Products(1)

mRNA Protein Name
NM_010305.1 NP_034435.1 guanine nucleotide-binding protein G(i) subunit alpha-1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25242222 MGI
Cellular Component GO Annotation Evidence Reference Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
16805845 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(i) subunit alpha-1

adenylate cyclase-inhibiting G alpha protein

guanine nucleotide binding protein, alpha inhibiting 1

heterotrimeric guanine nucleotide-binding protein 1b

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05534 GNAI1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22533 Gnai1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnai1 NCBI NCBI:2770