2. Gene
  3. Gjb3 - gap junction protein, beta 3 Gene

Gjb3 - gap junction protein, beta 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cx31; Cxnc; Cnx31; Gjb-3; D4Wsu144e

Gene ID: 14620 | Gene type: protein coding

About Gjb3

Summary

Predicted to enable gap junction channel activity. Acts upstream of or within placenta development. Located in cytoplasm and gap junction. Is expressed in several structures, including alimentary system; early conceptus; integumental system; reproductive system; and sensory organ. Used to study erythrokeratodermia variabilis. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 2B; autosomal recessive nonsyndromic deafness 1A; erythrokeratodermia variabilis; and erythrokeratodermia variabilis et progressiva 1. Orthologous to human GJB3 (Gap Junction Protein beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Gjb3 Products(2)

mRNA Protein Name
NM_001160012.2 NP_001153484.1 gap junction beta-3 protein
NM_008126.3 NP_032152.1 gap junction beta-3 protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18055446 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within placenta development IMP
IMP: Inferred from mutant phenotype
15895417 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
7889986 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
7889986 MGI
located in gap junction IDA
IDA: Inferred from direct assay
14595769 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction beta-3 protein

connexin c

connexin-31

gap junction membrane channel protein beta 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05448 GJB3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22183 Gjb3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjb3 NCBI NCBI:2707