2. Gene
  3. Gdf9 - growth differentiation factor 9 Gene

Gdf9 - growth differentiation factor 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gdf-9

Gene ID: 14566 | Gene type: protein coding

About Gdf9

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates ovarian function. Female mice that are homozygous null for this gene are sterile with impaired folliculogenesis. [provided by RefSeq, Jul 2016]

Gdf9 Products(1)

mRNA Protein Name
NM_008110.2 NP_032136.2 growth/differentiation factor 9 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of cell growth IMP
IMP: Inferred from mutant phenotype
17641088 MGI
acts upstream of or within negative regulation of cell growth IMP
IMP: Inferred from mutant phenotype
17641088 MGI
acts upstream of or within oocyte growth IMP
IMP: Inferred from mutant phenotype
17641088 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19480014 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth/differentiation factor 9

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05358 GDF9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17807 Gdf9 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24275 Gdf9 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gdf9 NCBI NCBI:2661