1. Gene
  2. Gpd1 - glycerol-3-phosphate dehydrogenase 1 (soluble) Gene

Gpd1 - glycerol-3-phosphate dehydrogenase 1 (soluble) Gene

Mus musculus

Also known as Gdc1; GPD-C; Gdc-1; GPDH-C

Gene ID: 14555 | Gene type: protein coding

About Gpd1

Summary

Enables glycerol-3-phosphate dehydrogenase [NAD+] activity. Acts upstream of or within several processes, including cellular response to cAMP; gluconeogenesis; and glycerophosphate shuttle. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; liver; and nervous system. Orthologous to human GPD1 (glycerol-3-phosphate dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Gpd1 Products(1)

mRNA Protein Name
NM_010271.3 NP_034401.1 glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables glycerol-3-phosphate dehydrogenase [NAD(P)+] activity IDA
IDA: Inferred from direct assay
6105153 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within NADH oxidation IMP
IMP: Inferred from mutant phenotype
11147825 MGI
acts upstream of or within cellular response to cAMP IDA
IDA: Inferred from direct assay
3027100 MGI
acts upstream of or within cellular response to tumor necrosis factor IDA
IDA: Inferred from direct assay
3027100 MGI
acts upstream of or within gluconeogenesis IMP
IMP: Inferred from mutant phenotype
12093800 MGI
acts upstream of or within glycerol-3-phosphate metabolic process IMP
IMP: Inferred from mutant phenotype
12093800 MGI
acts upstream of or within glycerophosphate shuttle IMP
IMP: Inferred from mutant phenotype
11147825 MGI
involved in glycerophosphate shuttle IMP
IMP: Inferred from mutant phenotype
25603051 MGI
acts upstream of or within positive regulation of glycolytic process IMP
IMP: Inferred from mutant phenotype
11147825 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
26049045 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

glycerolphosphate dehydrogenase 1, cytoplasmic adult

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpd1 NCBI NCBI:2819