Gart - phosphoribosylglycinamide formyltransferase Gene

Mus musculus

Also known as Gaps; Prgs

Gene ID: 14450 | Gene type: protein coding

About Gart

Summary

Enables phosphoribosylamine-glycine Ligase activity. Involved in purine ribonucleoside monophosphate biosynthetic process. Is active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase). [provided by Alliance of Genome Resources, Apr 2022]

Gart Products(2)

mRNA	Protein	Name
NM_001357351.1	NP_001344280.1	trifunctional purine biosynthetic protein adenosine-3
NM_010256.2	NP_034386.2	trifunctional purine biosynthetic protein adenosine-3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables phosphoribosylamine-glycine ligase activity	IDA IDA: Inferred from direct assay	8299947	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in 'de novo' AMP biosynthetic process	IDA IDA: Inferred from direct assay	8299947	MGI
involved in 'de novo' IMP biosynthetic process	IDA IDA: Inferred from direct assay	8299947	MGI
involved in 'de novo' XMP biosynthetic process	IDA IDA: Inferred from direct assay	8299947	MGI
involved in GMP biosynthetic process	IDA IDA: Inferred from direct assay	8299947	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cytosol	IDA IDA: Inferred from direct assay	8299947	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

trifunctional purine biosynthetic protein adenosine-3

glycinamide ribonucleotide synthetase

glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide formyltransferase

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05280	GART Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS18934	Gart Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25424	Gart Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gart	NCBI	NCBI:2618

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