2. Gene
  3. Gabra4 - gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 Gene

Gabra4 - gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gabra-4

Gene ID: 14397 | Gene type: protein coding

About Gabra4

Summary

Predicted to enable GABA-gated chloride ion channel activity; inhibitory extracellular ligand-gated ion channel activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and Chloride Channel activity. Acts upstream of or within central nervous system development. Predicted to be located in postsynaptic membrane. Predicted to be integral component of membrane. Predicted to be part of GABA-A receptor complex. Predicted to be active in dendrite membrane and postsynapse. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and spinal cord. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human GABRA4 (gamma-aminobutyric acid type A receptor subunit alpha4). [provided by Alliance of Genome Resources, Apr 2022]

Gabra4 Products(9)

mRNA Protein Name
NM_001359041.1 NP_001345970.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor
NM_001359043.1 NP_001345972.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 3
NM_001359044.1 NP_001345973.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 4 precursor
NM_001359045.1 NP_001345974.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 5 precursor
NM_001359046.1 NP_001345975.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 6 precursor
NM_001359047.1 NP_001345976.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 7 precursor
NM_001359048.1 NP_001345977.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 8 precursor
NM_001359050.1 NP_001345979.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 9 precursor
NM_010251.2 NP_034381.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 2 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within central nervous system development IMP
IMP: Inferred from mutant phenotype
17005728 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-aminobutyric acid receptor subunit alpha-4

GABA(A) receptor subunit alpha-4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05212 GABRA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20552 Gabra4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27061 Gabra4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gabra4 NCBI NCBI:2557