2. Gene
  3. Fem1b - fem 1 homolog b Gene

Fem1b - fem 1 homolog b Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA0396

Gene ID: 14155 | Gene type: protein coding

About Fem1b

Summary

Predicted to enable death receptor binding activity and ubiquitin ligase-substrate adaptor activity. Acts upstream of or within branching involved in prostate gland morphogenesis; epithelial cell maturation involved in prostate gland development; and protein ubiquitination. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Used to study type 2 diabetes mellitus. Orthologous to human FEM1B (fem-1 homolog B). [provided by Alliance of Genome Resources, Apr 2022]

Fem1b Products(1)

mRNA Protein Name
NM_010193.4 NP_034323.1 protein fem-1 homolog B
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18816836 MGI
enables ubiquitin-like ligase-substrate adaptor activity IDA
IDA: Inferred from direct assay
34562363 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within branching involved in prostate gland morphogenesis IMP
IMP: Inferred from mutant phenotype
18816836 MGI
acts upstream of or within epithelial cell maturation IMP
IMP: Inferred from mutant phenotype
18816836 MGI
acts upstream of or within epithelial cell maturation involved in prostate gland development IMP
IMP: Inferred from mutant phenotype
18816836 MGI
acts upstream of or within protein ubiquitination IDA
IDA: Inferred from direct assay
21723927 MGI
involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway IDA
IDA: Inferred from direct assay
34562363 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21723927 MGI
located in nucleus IDA
IDA: Inferred from direct assay
19796622 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein fem-1 homolog B

F1A-alpha

FEM1-beta

fem-1-like death receptor-binding protein alpha

fem-1-like in apoptotic pathway protein alpha

feminization 1 homolog b

mt-Fem

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W229874 EN106 99.92% Unkown
HY-143348 NJH-2-030 Chemical 98.74% Unkown
HY-168863 FF2049 / Unkown
HY-168865 E3 ligase Ligand 53 / Unkown
HY-RS04859 FEM1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22506 Fem1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29027 Fem1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fem1b NCBI NCBI:10116