2. Gene
  3. PAICS - Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase Gene

PAICS - Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Airc; Ade2h1

Gene ID: 140946 | Gene type: protein coding

About PAICS

Summary

Predicted to enable identical protein binding activity and phosphoribosylaminoimidazolesuccinocarboxamide synthase activity. Involved in G1/S transition of mitotic cell cycle. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase). [provided by Alliance of Genome Resources, Apr 2022]

PAICS Products(1)

mRNA Protein Name
NM_080910.3 NP_543186.1 bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in G1/S transition of mitotic cell cycle IEP
IEP: Inferred from expression pattern
7742366 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

multifunctional protein ADE2

AIR carboxylase-SAICAR synthetase

multifunctional protein ADE2-like

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148218 N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine / Unkown
HY-RS09980 PAICS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21010 Paics Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27527 Paics Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PAICS NCBI NCBI:10606