2. Gene
  3. Fancc - Fanconi anemia, complementation group C Gene

Fancc - Fanconi anemia, complementation group C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Facc

Gene ID: 14088 | Gene type: protein coding

About Fancc

Summary

Acts upstream of or within several processes, including brain morphogenesis; neuronal stem cell population maintenance; and removal of superoxide radicals. Predicted to be located in chromatin and cytosol. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including central nervous system; embryo mesenchyme; reproductive system; retina nuclear layer; and skeleton. Used to study Fanconi anemia complementation group C. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple); acute myeloid leukemia; aspirin-induced respiratory disease; pancreatic cancer; and pancytopenia. Orthologous to human FANCC (FA complementation group C). [provided by Alliance of Genome Resources, Apr 2022]

Fancc Products(5)

mRNA Protein Name
NM_001042673.2 NP_001036138.1 Fanconi anemia group C protein homolog isoform 1
NM_001282942.1 NP_001269871.1 Fanconi anemia group C protein homolog isoform 2
NM_001347514.1 NP_001334443.1 Fanconi anemia group C protein homolog isoform 3
NM_001347515.1 NP_001334444.1 Fanconi anemia group C protein homolog isoform 4 precursor
NM_007985.3 NP_032011.2 Fanconi anemia group C protein homolog isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within brain morphogenesis IGI
IGI: Inferred from genetic interaction
24483844 MGI
acts upstream of or within cellular response to oxidative stress IGI
IGI: Inferred from genetic interaction
24483844 MGI
acts upstream of or within gamete generation IMP
IMP: Inferred from mutant phenotype
8630504 MGI
acts upstream of or within germ cell development IMP
IMP: Inferred from mutant phenotype
8704201 MGI
acts upstream of or within myeloid cell homeostasis IGI
IGI: Inferred from genetic interaction
11493445 MGI
acts upstream of or within myeloid cell homeostasis IMP
IMP: Inferred from mutant phenotype
11493445 MGI
acts upstream of or within neuronal stem cell population maintenance IGI
IGI: Inferred from genetic interaction
24483844 MGI
acts upstream of or within nucleotide-excision repair IMP
IMP: Inferred from mutant phenotype
8704201 MGI
acts upstream of or within removal of superoxide radicals IGI
IGI: Inferred from genetic interaction
11493445 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Fanconi anemia group C protein homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04734 FANCC Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20402 Fancc Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26911 Fancc Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fancc NCBI NCBI:2176