2. Gene
  3. Ttbk2 - tau tubulin kinase 2 Gene

Ttbk2 - tau tubulin kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TTK; Ttbk; Ttbk1; mKIAA0847; 2610507N02Rik; B930008N24Rik

Gene ID: 140810 | Gene type: protein coding

About Ttbk2

Summary

Enables protein serine/threonine kinase activity. Involved in cilium assembly; hindbrain development; and smoothened signaling pathway. Acts upstream of or within several processes, including embryonic brain development; nervous system development; and positive regulation of non-motile cilium assembly. Located in centriole; ciliary basal body; and ciliary transition zone. Is expressed in nervous system. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK2 (tau tubulin kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ttbk2 Products(3)

mRNA Protein Name
NM_001024856.2 NP_001020027.1 tau-tubulin kinase 2 isoform 2
NM_001024857.2 NP_001020028.1 tau-tubulin kinase 2 isoform 2
NM_080788.3 NP_542966.2 tau-tubulin kinase 2 isoform 1
Protein Preferred Names Protein Names

tau-tubulin kinase 2

protein bartleby

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-172542 TTBK1/2-IN-1 Inhibitor / Unkown
HY-172543 TTBK1/2-IN-2 Inhibitor / Unkown
HY-172544 TTBK1/2-IN-3 Inhibitor / Unkown
HY-172545 AMG28 Inhibitor / Unkown
HY-RS15194 TTBK2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21071 Ttbk2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27588 Ttbk2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttbk2 NCBI NCBI:146057