2. Gene
  3. Tmprss3 - transmembrane protease, serine 3 Gene

Tmprss3 - transmembrane protease, serine 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 140765 | Gene type: protein coding

About Tmprss3

Summary

Predicted to enable Sodium Channel regulator activity. Involved in sensory perception of sound. Located in endoplasmic reticulum and neuronal cell body. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 8 and sensorineural hearing loss. Orthologous to human TMPRSS3 (transmembrane serine protease 3). [provided by Alliance of Genome Resources, Apr 2022]

Tmprss3 Products(2)

mRNA Protein Name
NM_001163776.1 NP_001157248.1 transmembrane protease serine 3 isoform 1
NM_080727.2 NP_542765.2 transmembrane protease serine 3 isoform 2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in sensory perception of sound IMP
IMP: Inferred from mutant phenotype
21454591 MGI
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
21454591 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
17918732 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protease serine 3

transmembrane proteinase serine 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14770 TMPRSS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14771 TMPRSS4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21265 Tmprss3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27784 Tmprss3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmprss3 NCBI NCBI:64699