2. Gene
  3. Abcb6 - ATP binding cassette subfamily B member 6 Gene

Abcb6 - ATP binding cassette subfamily B member 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as MTABC3

Gene ID: 140669 | Gene type: protein coding

About Abcb6

Summary

Predicted to enable several functions, including ABC-type heme transporter activity; ATP binding activity; and heme binding activity. Involved in cellular copper ion homeostasis. Located in endosome membrane and mitochondrion. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Orthologous to human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Abcb6 Products(1)

mRNA Protein Name
NM_080582.1 NP_542149.1 ATP-binding cassette sub-family B member 6
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in intracellular copper ion homeostasis IDA
IDA: Inferred from direct assay
18160489 RGD
Cellular Component GO Annotation Evidence Reference Source
located in early endosome membrane IDA
IDA: Inferred from direct assay
18160489 RGD
located in endolysosome membrane IDA
IDA: Inferred from direct assay
18160489 RGD
located in late endosome membrane IDA
IDA: Inferred from direct assay
18160489 RGD
located in lysosomal membrane IDA
IDA: Inferred from direct assay
18160489 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-binding cassette sub-family B member 6

ATP-binding cassette sub-family B member 6, mitochondrial

ABC-type heme transporter ABCB6

ATP-binding cassette, sub-family B (MDR/TAP), member 6

ATP-binding cassette, subfamily B (MDR/TAP), member 6

mammalian mitochondrial ABC protein 3

ubiquitously-expressed mammalian ABC half transporter

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00053 ABCB6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20354 Abcb6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26863 Abcb6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcb6 NCBI NCBI:10058