2. Gene
  3. Siah2 - siah E3 ubiquitin protein ligase 2 Gene

Siah2 - siah E3 ubiquitin protein ligase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 140593 | Gene type: protein coding

About Siah2

Summary

Enables ubiquitin conjugating enzyme binding activity. Involved in regulation of protein ubiquitination. Located in several cellular components, including cytosol; early endosome; and neuronal cell body. Orthologous to human SIAH2 (siah E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Siah2 Products(1)

mRNA Protein Name
NM_134457.2 NP_604452.1 E3 ubiquitin-protein ligase SIAH2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11786535 RGD
enables ubiquitin conjugating enzyme binding IDA
IDA: Inferred from direct assay
11786535 RGD
Biological Process GO Annotation Evidence Reference Source
involved in regulation of protein ubiquitination IDA
IDA: Inferred from direct assay
11786535 RGD
Cellular Component GO Annotation Evidence Reference Source
located in early endosome IDA
IDA: Inferred from direct assay
11786535 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
11786535 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase SIAH2

RING-type E3 ubiquitin transferase SIAH2

seven in absentia 2

seven in absentia homolog 2

siah-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12892 SIAH2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21046 Siah2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27564 Siah2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Siah2 NCBI NCBI:6478