2. Gene
  3. Ryk - receptor-like tyrosine kinase Gene

Ryk - receptor-like tyrosine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 140585 | Gene type: protein coding

About Ryk

Summary

Predicted to enable Wnt-activated receptor activity; Wnt-protein binding activity; and Frizzled binding activity. Predicted to be involved in several processes, including nervous system development; positive regulation of MAPK cascade; and positive regulation of kinase activity. Predicted to act upstream of or within several processes, including generation of neurons; negative chemotaxis; and skeletal system morphogenesis. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Orthologous to human RYK (receptor like tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Ryk Products(1)

mRNA Protein Name
NM_080402.2 NP_536327.1 tyrosine-protein kinase RYK precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
23517308 RGD
involved in axonogenesis IGI
IGI: Inferred from genetic interaction
23517308 RGD
involved in positive regulation of cell proliferation in midbrain IMP
IMP: Inferred from mutant phenotype
23517308 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein kinase RYK

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12367 RYK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18743 Ryk Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25230 Ryk Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ryk NCBI NCBI:6259