2. Gene
  3. Igf2bp1 - insulin-like growth factor 2 mRNA binding protein 1 Gene

Igf2bp1 - insulin-like growth factor 2 mRNA binding protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as IMP1; Zbp1; Crdbp; ZBP-1; CRD-BP; Neilsen; D11Moh45; mir-3063; D11Moh40e; D030026A21Rik

Gene ID: 140486 | Gene type: protein coding

About Igf2bp1

Summary

Predicted to enable mRNA 3'-UTR binding activity; mRNA 5'-UTR binding activity; and translation regulator activity. Acts upstream of or within neuronal stem cell population maintenance and pallium cell proliferation in forebrain. Predicted to be located in several cellular components, including cytoplasmic stress granule; dendritic spine; and neuronal cell body. Predicted to be part of CRD-mediated mRNA stability complex and ribonucleoprotein complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including early conceptus; eye; forebrain; gonad; and intestine. Orthologous to human IGF2BP1 (Insulin like growth factor 2 mRNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Igf2bp1 Products(5)

mRNA Protein Name
NM_001401454.1 NP_001388383.1 insulin-like growth factor 2 mRNA-binding protein 1 isoform 2
NM_001401455.1 NP_001388384.1 insulin-like growth factor 2 mRNA-binding protein 1 isoform 3
NM_001401456.1 NP_001388385.1 insulin-like growth factor 2 mRNA-binding protein 1 isoform 4
NM_001401457.1 NP_001388386.1 insulin-like growth factor 2 mRNA-binding protein 1 isoform 4
NM_009951.4 NP_034081.1 insulin-like growth factor 2 mRNA-binding protein 1 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within neuronal stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
24192035 MGI
acts upstream of or within pallium cell proliferation in forebrain IMP
IMP: Inferred from mutant phenotype
24192035 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin-like growth factor 2 mRNA-binding protein 1

IGF-II mRNA-binding protein 1

IGF2 mRNA-binding protein 1

VICKZ family member 1

coding region determinant binding protein

insulin-like growth factor 2 mRNA binding protein 1 dN CRDBP-2

insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-144873 AVJ16 Inducer 99.60% Unkown
HY-156110 IGF2BP1-IN-1 Inhibitor 99.94% Unkown
HY-RS06619 IGF2BP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16849 Igf2bp1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23290 Igf2bp1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igf2bp1 NCBI NCBI:10642