2. Gene
  3. Enam - enamelin Gene

Enam - enamelin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as abte

Gene ID: 13801 | Gene type: protein coding

About Enam

Summary

A structural constituent of tooth enamel. Acts upstream of or within several processes, including ameloblast differentiation; amelogenesis; and positive regulation of enamel mineralization. Located in extracellular matrix. Is expressed in lower jaw molar; molar enamel organ; and upper jaw incisor. Used to study amelogenesis imperfecta type 1B. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1B and amelogenesis imperfecta type 1C. Orthologous to human ENAM (enamelin). [provided by Alliance of Genome Resources, Apr 2022]

Enam Products(1)

mRNA Protein Name
NM_017468.3 NP_059496.1 enamelin precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables structural constituent of tooth enamel IDA
IDA: Inferred from direct assay
24603688 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within ameloblast differentiation IMP
IMP: Inferred from mutant phenotype
24603688 MGI
acts upstream of or within amelogenesis IMP
IMP: Inferred from mutant phenotype
15649948 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: Inferred from mutant phenotype
15271968 MGI
acts upstream of or within positive regulation of enamel mineralization IMP
IMP: Inferred from mutant phenotype
24603688 MGI
acts upstream of or within regulation of cell morphogenesis IMP
IMP: Inferred from mutant phenotype
24603688 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
24603688 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

enamelin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04368 ENAM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19597 Enam Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26093 Enam Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Enam NCBI NCBI:10117