Emx2 - empty spiracles homeobox 2 Gene

Mus musculus

Also known as Pdo

Gene ID: 13797 | Gene type: protein coding

About Emx2

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including anterior/posterior pattern specification; forebrain development; and ureter morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; future brain; genitourinary system; hindlimb phalanx; and nose. Orthologous to human EMX2 (empty spiracles homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Emx2 Products(1)

mRNA	Protein	Name
NM_010132.2	NP_034262.2	homeobox protein EMX2

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within anterior/posterior pattern specification	IGI IGI: Inferred from genetic interaction	15917450	MGI
acts upstream of or within anterior/posterior pattern specification	IMP IMP: Inferred from mutant phenotype	12196586	MGI
acts upstream of or within brain development	IMP IMP: Inferred from mutant phenotype	12091317	MGI
acts upstream of or within cell proliferation in forebrain	IMP IMP: Inferred from mutant phenotype	10729342	MGI
acts upstream of or within cerebral cortex development	IGI IGI: Inferred from genetic interaction	12764040	MGI
acts upstream of or within cerebral cortex regionalization	IGI IGI: Inferred from genetic interaction	15147765	MGI
acts upstream of or within cerebral cortex regionalization	IMP IMP: Inferred from mutant phenotype	12764040	MGI
acts upstream of or within dentate gyrus development	IMP IMP: Inferred from mutant phenotype	10729342	MGI
acts upstream of or within forebrain cell migration	IMP IMP: Inferred from mutant phenotype	10729342	MGI
acts upstream of or within forebrain development	IGI IGI: Inferred from genetic interaction	15917450	MGI
acts upstream of or within forebrain development	IMP IMP: Inferred from mutant phenotype	15294144	MGI
acts upstream of or within neuron differentiation	IMP IMP: Inferred from mutant phenotype	12561075	MGI
acts upstream of or within neuron migration	IMP IMP: Inferred from mutant phenotype	10729342	MGI
acts upstream of or within regulation of gene expression	IMP IMP: Inferred from mutant phenotype	12764040	MGI
acts upstream of or within response to xenobiotic stimulus	IDA IDA: Inferred from direct assay	9098922	MGI
involved in stereocilium bundle organization	IMP IMP: Inferred from mutant phenotype	34001891	MGI
acts upstream of or within ureter morphogenesis	IGI IGI: Inferred from genetic interaction	21731775	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

homeobox protein EMX2

empty spiracles homolog 2

empty spiracles-like protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04364	EMX2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20728	Emx2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27240	Emx2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Emx2	NCBI	NCBI:2018

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