Emx1 - empty spiracles homeobox 1 Gene

Mus musculus

Gene ID: 13796 | Gene type: protein coding

About Emx1

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including nervous system development; neuroepithelial cell differentiation; and regulation of oligodendrocyte progenitor proliferation. Located in nucleus. Is expressed in several structures, including genitourinary system; ileum; nervous system; sensory organ; and surface ectoderm. Orthologous to human EMX1 (empty spiracles homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Emx1 Products(1)

mRNA	Protein	Name
NM_010131.2	NP_034261.1	homeobox protein EMX1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	29263200	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within brain development	IMP IMP: Inferred from mutant phenotype	12091317	MGI
acts upstream of or within brain morphogenesis	IGI IGI: Inferred from genetic interaction	23178126	MGI
acts upstream of or within cerebral cortex development	IGI IGI: Inferred from genetic interaction	12764040	MGI
acts upstream of or within cerebral cortex development	IMP IMP: Inferred from mutant phenotype	16892058	MGI
acts upstream of or within cerebral cortex neuron differentiation	IGI IGI: Inferred from genetic interaction	23178126	MGI
acts upstream of or within cerebral cortex regionalization	IGI IGI: Inferred from genetic interaction	15147765	MGI
acts upstream of or within homeostasis of number of cells	IGI IGI: Inferred from genetic interaction	25100583	MGI
acts upstream of or within in utero embryonic development	IGI IGI: Inferred from genetic interaction	23861879	MGI
acts upstream of or within neuroepithelial cell differentiation	IGI IGI: Inferred from genetic interaction	25100583	MGI
acts upstream of or within neuron differentiation	IMP IMP: Inferred from mutant phenotype	12561075	MGI
acts upstream of or within neuron projection extension	IGI IGI: Inferred from genetic interaction	23861879	MGI
acts upstream of or within post-embryonic development	IMP IMP: Inferred from mutant phenotype	16892058	MGI
acts upstream of or within radial glial cell differentiation	IGI IGI: Inferred from genetic interaction	25100583	MGI
acts upstream of or within regulation of oligodendrocyte progenitor proliferation	IGI IGI: Inferred from genetic interaction	25100583	MGI
acts upstream of or within response to xenobiotic stimulus	IDA IDA: Inferred from direct assay	9098922	MGI
acts upstream of or within telencephalon development	IGI IGI: Inferred from genetic interaction	25100583	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	29263200	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

homeobox protein EMX1

empty spiracles homolog 1

empty spiracles-like protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04363	EMX1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21335	Emx1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27854	Emx1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Emx1	NCBI	NCBI:2016

Name
Email *

	Sorry, but the email address you supplied was invalid.