2. Gene
  3. Eef1a2 - eukaryotic translation elongation factor 1 alpha 2 Gene

Eef1a2 - eukaryotic translation elongation factor 1 alpha 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as S1; STN; wst; Eef1a; EEF1AL; wasted; EF-1-alpha-2

Gene ID: 13628 | Gene type: protein coding

About Eef1a2

Summary

Enables translation elongation factor activity. Acts upstream of or within positive regulation of apoptotic process and translational elongation. Located in cytoplasm. Part of eukaryotic translation elongation factor 1 complex. Is active in synapse. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and integumental system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 38; developmental and epileptic encephalopathy 33; and ovarian Cancer. Orthologous to human EEF1A2 (eukaryotic translation elongation factor 1 alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Eef1a2 Products(1)

mRNA Protein Name
NM_007906.3 NP_031932.1 elongation factor 1-alpha 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables translation elongation factor activity IDA
IDA: Inferred from direct assay
9588196 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
11724805 MGI
acts upstream of or within translational elongation IDA
IDA: Inferred from direct assay
9588196 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15013623 MGI
part of eukaryotic translation elongation factor 1 complex IDA
IDA: Inferred from direct assay
9588196 MGI
is active in synapse EXP
EXP: Inferred from Experiment
16452087 MGI
is active in synapse IDA
IDA: Inferred from direct assay
16452087 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

elongation factor 1-alpha 2

eukaryotic elongation factor 1 A-2

statin-S1

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16050 Plitidepsin Inhibitor 99.99% Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-120118 Metarrestin Inhibitor 99.90% Phase 1
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04175 EEF1A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04176 EEF1B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19059 Eef1b2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21848 Eef1a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24785 Eef1a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25549 Eef1b2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eef1a2 NCBI NCBI:1917