2. Gene
  3. Dmp1 - dentin matrix protein 1 Gene

Dmp1 - dentin matrix protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PP; AG1; Dmp; DMP-1

Gene ID: 13406 | Gene type: protein coding

About Dmp1

Summary

Enables extracellular matrix binding activity. Acts upstream of or within extracellular matrix organization; positive regulation of cell-substrate adhesion; and regulation of enamel mineralization. Located in extracellular matrix and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; immune system; nervous system; and stylopod. Used to study autosomal recessive hypophosphatemic rickets. Orthologous to human DMP1 (dentin matrix acidic phosphoprotein 1). [provided by Alliance of Genome Resources, Apr 2022]

Dmp1 Products(2)

mRNA Protein Name
NM_001359013.1 NP_001345942.1 dentin matrix acidic phosphoprotein 1 precursor
NM_016779.2 NP_058059.2 dentin matrix acidic phosphoprotein 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables extracellular matrix binding IDA
IDA: Inferred from direct assay
18757743 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
18757743 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
18757743 MGI
acts upstream of or within regulation of enamel mineralization IDA
IDA: Inferred from direct assay
16014627 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
32256524 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
19001636 MGI
located in nucleus IDA
IDA: Inferred from direct assay
19001636 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dentin matrix acidic phosphoprotein 1

serine rich acidic phosphoprotein

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03826 DMP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03833 DMTF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19893 Dmp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26393 Dmp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dmp1 NCBI NCBI:1758