2. Gene
  3. Dlx6 - distal-less homeobox 6 Gene

Dlx6 - distal-less homeobox 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 13396 | Gene type: protein coding

About Dlx6

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; positive regulation of epithelial cell proliferation; and roof of mouth development. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb; and sensory organ. Used to study split hand-foot malformation 1. Orthologous to human DLX6 (distal-less homeobox 6). [provided by Alliance of Genome Resources, Apr 2022]

Dlx6 Products(1)

mRNA Protein Name
NM_010057.2 NP_034187.1 homeobox protein DLX-6
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anatomical structure formation involved in morphogenesis IGI
IGI: Inferred from genetic interaction
17878916 MGI
acts upstream of or within embryonic limb morphogenesis IGI
IGI: Inferred from genetic interaction
12112878 MGI
acts upstream of or within epithelial cell differentiation IGI
IGI: Inferred from genetic interaction
17878916 MGI
acts upstream of or within head development IGI
IGI: Inferred from genetic interaction
15306564 MGI
acts upstream of or within inner ear morphogenesis IGI
IGI: Inferred from genetic interaction
16900517 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IGI
IGI: Inferred from genetic interaction
16900517 MGI
acts upstream of or within roof of mouth development IGI
IGI: Inferred from genetic interaction
17420000 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein DLX-6

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03817 DLX6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22140 Dlx6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28661 Dlx6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dlx6 NCBI NCBI:1750