2. Gene
  3. Ackr1 - atypical chemokine receptor 1 (Duffy blood group) Gene

Ackr1 - atypical chemokine receptor 1 (Duffy blood group) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FY; Dfy; GPD; Darc; CCBP1; CD234; ESTM35

Gene ID: 13349 | Gene type: protein coding

About Ackr1

Summary

Predicted to enable C-C chemokine binding activity. Acts upstream of or within inflammatory response and regulation of chemokine production. Predicted to be located in endosome and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including genitourinary system; hemolymphoid system; lung; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Plasmodium vivax malaria and malaria. Orthologous to human ACKR1 (atypical Chemokine Receptor 1 (Duffy blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Ackr1 Products(1)

mRNA Protein Name
NM_010045.3 NP_034175.2 atypical chemokine receptor 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
10961863 MGI
acts upstream of or within regulation of chemokine production IMP
IMP: Inferred from mutant phenotype
20643340 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

atypical chemokine receptor 1

Duffy antigen receptor for chemokines

Duffy blood group, chemokine receptor

duffy antigen/chemokine receptor

glycoprotein D

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00160 ACKR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18799 Ackr1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25288 Ackr1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ackr1 NCBI NCBI:2532