2. Gene
  3. Dhx9 - DEAH (Asp-Glu-Ala-His) box polypeptide 9 Gene

Dhx9 - DEAH (Asp-Glu-Ala-His) box polypeptide 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as RHA; Ddx9; HEL-5; NDHII; mHEL-5

Gene ID: 13211 | Gene type: protein coding

About Dhx9

Summary

Enables regulatory region RNA binding activity. Involved in positive regulation of interleukin-18 production; pyroptosis; and regulation of defense response. Acts upstream of or within cellular response to heat and circadian rhythm. Located in nucleolus. Is expressed in several structures, including alimentary system; central nervous system; lung; sensory organ; and vibrissa. Orthologous to human DHX9 (DExH-box helicase 9). [provided by Alliance of Genome Resources, Apr 2022]

Dhx9 Products(2)

mRNA Protein Name
NM_001405509.1 NP_001392438.1 ATP-dependent RNA helicase A isoform 1
NM_007842.3 NP_031868.2 ATP-dependent RNA helicase A isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18068128 MGI
enables regulatory region RNA binding IDA
IDA: Inferred from direct assay
28355180 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to heat IDA
IDA: Inferred from direct assay
18755693 MGI
acts upstream of or within circadian rhythm IMP
IMP: Inferred from mutant phenotype
22767893 MGI
involved in positive regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
28636595 MGI
involved in positive regulation of innate immune response IMP
IMP: Inferred from mutant phenotype
28636595 MGI
involved in positive regulation of interleukin-18 production IMP
IMP: Inferred from mutant phenotype
28636595 MGI
involved in pyroptotic inflammatory response IMP
IMP: Inferred from mutant phenotype
28636595 MGI
involved in regulation of defense response to virus by host IMP
IMP: Inferred from mutant phenotype
28636595 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleolus IDA
IDA: Inferred from direct assay
14729462 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-dependent RNA helicase A

D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 9

DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 9

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9

DEAH box protein 9

RNA helicase A

leukophysin

nuclear DNA helicase II

Related Agents

Pre-clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-156784 ATX968 Inhibitor 98.83% Unkown
HY-156782 DHX9-IN-1 Inhibitor 98.33% Unkown
HY-160007 DHX9-IN-3 Inhibitor 99.78% Unkown
HY-157604 DHX9-IN-9 Inhibitor 99.79% Unkown
HY-160009 DHX9-IN-5 Inhibitor 99.75% Unkown
HY-160008 DHX9-IN-4 Inhibitor / Unkown
HY-160010 DHX9-IN-6 Inhibitor / Unkown
HY-157602 DHX9-IN-8 Inhibitor / Unkown
HY-157603 DHX9-IN-7 Inhibitor / Unkown
HY-157605 DHX9-IN-11 Inhibitor / Unkown
HY-157606 DHX9-IN-13 Inhibitor / Unkown
HY-157607 DHX9-IN-15 Inhibitor / Unkown
HY-157608 DHX9-IN-10 Inhibitor / Unkown
HY-157609 DHX9-IN-12 Inhibitor / Unkown
HY-157610 DHX9-IN-14 Inhibitor / Unkown
HY-157611 DHX9-IN-17 Inhibitor / Unkown
HY-157612 DHX9-IN-16 Inhibitor / Unkown
HY-170684 DHX9-IN-19 Inhibitor / Unkown
HY-RS03761 DHX9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18237 Dhx9 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24716 Dhx9 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dhx9 NCBI NCBI:1660