Dnajc5 - DnaJ heat shock protein family (Hsp40) member C5 Gene

Mus musculus

Also known as Csp; 2610314I24Rik

Gene ID: 13002 | Gene type: protein coding

About Dnajc5

Summary

Predicted to enable ATP-dependent protein binding activity. Involved in chaperone-mediated protein folding and regulation of synaptic vesicle cycle. Acts upstream of or within negative regulation of neuron apoptotic process. Located in neuromuscular junction and synaptic vesicle. Is active in presynapse. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 4B. Orthologous to human DNAJC5 (DnaJ heat shock protein family (HSP40) member C5). [provided by Alliance of Genome Resources, Apr 2022]

Dnajc5 Products(3)

mRNA	Protein	Name
NM_001271584.1	NP_001258513.1	dnaJ homolog subfamily C member 5
NM_001271585.1	NP_001258514.1	dnaJ homolog subfamily C member 5
NM_016775.3	NP_058055.1	dnaJ homolog subfamily C member 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25253725	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in chaperone-mediated protein folding	IDA IDA: Inferred from direct assay	21151134	MGI
involved in chaperone-mediated protein folding	IEP IEP: Inferred from expression pattern	21151134	MGI
involved in chaperone-mediated protein folding	IMP IMP: Inferred from mutant phenotype	21151134	MGI
acts upstream of or within negative regulation of neuron apoptotic process	IGI IGI: Inferred from genetic interaction	16269331	MGI
acts upstream of neuron apoptotic process	IGI IGI: Inferred from genetic interaction	16269331	MGI
involved in regulation of synaptic vesicle cycle	IDA IDA: Inferred from direct assay	22500637	MGI
involved in regulation of synaptic vesicle cycle	IEP IEP: Inferred from expression pattern	22500637	MGI
involved in regulation of synaptic vesicle cycle	IMP IMP: Inferred from mutant phenotype	22500637	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in neuromuscular junction	IDA IDA: Inferred from direct assay	22500637	MGI
is active in neuromuscular junction	IEP IEP: Inferred from expression pattern	22500637	MGI
is active in neuromuscular junction	IMP IMP: Inferred from mutant phenotype	22500637	MGI
is active in presynapse	IDA IDA: Inferred from direct assay	21151134	MGI
is active in presynapse	IEP IEP: Inferred from expression pattern	21151134	MGI
is active in presynapse	IMP IMP: Inferred from mutant phenotype	21151134	MGI
located in synaptic vesicle	IDA IDA: Inferred from direct assay	16407767	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dnaJ homolog subfamily C member 5

DnaJ (Hsp40) homolog, subfamily C, member 5

cysteine string protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03886	DNAJC5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21117	Dnajc5 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27636	Dnajc5 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dnajc5	NCBI	NCBI:80331

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