2. Gene
  3. Crhbp - corticotropin releasing hormone binding protein Gene

Crhbp - corticotropin releasing hormone binding protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CRH-BP

Gene ID: 12919 | Gene type: protein coding

About Crhbp

Summary

Enables corticotropin-releasing hormone binding activity. Involved in several processes, including cellular response to estradiol stimulus; cellular response to organonitrogen compound; and maternal aggressive behavior. Acts upstream of or within hormone metabolic process. Located in extracellular space and nucleus. Is expressed in adrenal gland; central nervous system; eye; hemolymphoid system gland; and lung. Human ortholog(s) of this gene implicated in mental depression. Orthologous to human CRHBP (corticotropin releasing hormone binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Crhbp Products(1)

mRNA Protein Name
NM_198408.3 NP_940800.1 corticotropin-releasing factor-binding protein precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables corticotropin-releasing hormone binding IDA
IDA: Inferred from direct assay
7556876 MGI
enables corticotropin-releasing hormone binding IPI
IPI: Inferred from physical interaction
12895416 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to cAMP IDA
IDA: Inferred from direct assay
15976007 MGI
involved in cellular response to calcium ion IDA
IDA: Inferred from direct assay
15976007 MGI
involved in cellular response to estradiol stimulus IDA
IDA: Inferred from direct assay
15345745 MGI
involved in cellular response to gonadotropin-releasing hormone IDA
IDA: Inferred from direct assay
15976007 MGI
involved in cellular response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
15976007 MGI
acts upstream of or within hormone metabolic process IDA
IDA: Inferred from direct assay
7556876 MGI
involved in maternal aggressive behavior IMP
IMP: Inferred from mutant phenotype
18929624 MGI
involved in regulation of NMDA receptor activity IDA
IDA: Inferred from direct assay
12895416 MGI
involved in synaptic transmission, dopaminergic IDA
IDA: Inferred from direct assay
12895416 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
15976007 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15976007 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

corticotropin-releasing factor-binding protein

CRF-BP

CRF-binding protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03167 CRHBP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19425 Crhbp Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25916 Crhbp Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crhbp NCBI NCBI:1393