2. Gene
  3. Cox4i1 - cytochrome c oxidase subunit 4I1 Gene

Cox4i1 - cytochrome c oxidase subunit 4I1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as COX; Cox4; IV-1; COXIV; Cox4a; COX IV-1

Gene ID: 12857 | Gene type: protein coding

About Cox4i1

Summary

Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in cytosol and mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COX4I1 (cytochrome c oxidase subunit 4I1). [provided by Alliance of Genome Resources, Apr 2022]

Cox4i1 Products(2)

mRNA Protein Name
NM_001293559.1 NP_001280488.1 cytochrome c oxidase subunit 4 isoform 1, mitochondrial isoform 2
NM_009941.3 NP_034071.2 cytochrome c oxidase subunit 4 isoform 1, mitochondrial isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20959514 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
28376086 MGI
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
12910269 MGI
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
17923681 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
11940593 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome c oxidase subunit 4 isoform 1, mitochondrial

cytochrome c oxidase polypeptide IV

cytochrome c oxidase subunit IV

cytochrome c oxidase, subunit IVa

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03064 COX4I1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19251 Cox4i1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25740 Cox4i1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cox4i1 NCBI NCBI:1327