2. Gene
  3. Col7a1 - collagen, type VII, alpha 1 Gene

Col7a1 - collagen, type VII, alpha 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 12836 | Gene type: protein coding

About Col7a1

Summary

Enables identical protein binding activity. Predicted to act upstream of or within cell adhesion and negative regulation of peptidase activity. Located in basement membrane. Is expressed in glomerular basement membrane of mature renal corpuscle; pigmented retinal epithelium; skin; and surface ectoderm. Used to study recessive dystrophic epidermolysis bullosa. Human ortholog(s) of this gene implicated in epidermolysis bullosa dystrophica (multiple) and nonsyndromic congenital nail disorder 8. Orthologous to human COL7A1 (Collagen type VII alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col7a1 Products(1)

mRNA Protein Name
NM_007738.4 NP_031764.2 collagen alpha-1(VII) chain precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
21570975 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basement membrane IDA
IDA: Inferred from direct assay
18757743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-1(VII) chain

LC collagen

long-chain collagen

procollagen, type VII, alpha 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02997 COL7A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-162862 JAK-IN-38 / Unkown
HY-RS18704 Col7a1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25191 Col7a1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Col7a1 NCBI NCBI:1294