2. Gene
  3. Col6a3 - collagen, type VI, alpha 3 Gene

Col6a3 - collagen, type VI, alpha 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Col6a-3

Gene ID: 12835 | Gene type: protein coding

About Col6a3

Summary

Predicted to be an extracellular matrix structural constituent conferring tensile strength. Located in extracellular matrix; extracellular space; and sarcolemma. Part of Collagen trimer. Is expressed in several structures, including brain meninges; cardiovascular system; embryo mesenchyme; genitourinary system; and musculoskeletal system. Used to study Ullrich congenital muscular dystrophy and congenital muscular dystrophy. Human ortholog(s) of this gene implicated in Ullrich congenital muscular dystrophy; dystonia 27; and muscular dystrophy. Orthologous to human COL6A3 (Collagen type VI alpha 3 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col6a3 Products(2)

mRNA Protein Name
NM_001243008.1 NP_001229937.1 collagen alpha-3(VI) chain isoform 1 precursor
NM_001243009.1 NP_001229938.1 collagen alpha-3(VI) chain isoform 2 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within neuron apoptotic process IDA
IDA: Inferred from direct assay
21459131 MGI
acts upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: Inferred from direct assay
21459131 MGI
acts upstream of or within response to UV IDA
IDA: Inferred from direct assay
21459131 MGI
Cellular Component GO Annotation Evidence Reference Source
part of collagen trimer IDA
IDA: Inferred from direct assay
24563484 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
8806434 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
10444069 MGI
located in sarcolemma IDA
IDA: Inferred from direct assay
16810681 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-3(VI) chain

collagen alpha 3 chain type VI

collagen alpha3(VI)

procollagen, type VI, alpha 3

type VI collagen alpha 3 subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02994 COL6A3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18560 Col6a3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25042 Col6a3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Col6a3 NCBI NCBI:1293