2. Gene
  3. Cnp - 2',3'-cyclic nucleotide 3' phosphodiesterase Gene

Cnp - 2',3'-cyclic nucleotide 3' phosphodiesterase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cnp1; Cnp-1; CNPase

Gene ID: 12799 | Gene type: protein coding

About Cnp

Summary

Enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity. Acts upstream of or within adult locomotory behavior; neurogenesis; and response to toxic substance. Located in cytoplasm; membrane; and myelin sheath. Is expressed in adrenal gland; central nervous system; gut; peripheral nervous system; and reproductive system. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 20; multiple sclerosis; and schizophrenia. Orthologous to human CNP (2',3'-cyclic nucleotide 3' phosphodiesterase). [provided by Alliance of Genome Resources, Apr 2022]

Cnp Products(2)

mRNA Protein Name
NM_001146318.1 NP_001139790.1 2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform 1
NM_009923.2 NP_034053.2 2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IDA
IDA: Inferred from direct assay
12590258 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within adult locomotory behavior IMP
IMP: Inferred from mutant phenotype
12590258 MGI
acts upstream of or within axonogenesis IMP
IMP: Inferred from mutant phenotype
12590258 MGI
acts upstream of or within oligodendrocyte differentiation IMP
IMP: Inferred from mutant phenotype
19139271 MGI
acts upstream of or within response to toxic substance IDA
IDA: Inferred from direct assay
20578039 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
29350434 MGI
located in membrane IDA
IDA: Inferred from direct assay
12590258 MGI
located in myelin sheath IDA
IDA: Inferred from direct assay
24101522 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

2',3'-cyclic-nucleotide 3'-phosphodiesterase

cyclic nucleotide phosphodiesterase 1

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P3503 Vosoritide Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-119689 Umibecestat Inhibitor 99.81% Phase 3
HY-P3624 Cenderitide Agonist 99.84% Phase 2
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1237 C-Type Natriuretic Peptide (CNP) (1-22), human Inhibitor 99.41% Unkown
HY-P1237A C-Type Natriuretic Peptide (CNP) (1-22), human TFA 98.10% Unkown
HY-153102 G3-CNP 99.62% Unkown
HY-P5127 CNP-38 99.63% Unkown
HY-143316 NPR-C activator 1 Activator 99.30% Unkown
HY-P1556A Vasonatrin Peptide (VNP) TFA 98.79% Unkown
HY-15911 CNP-AFU 99.76% Unkown
HY-137672A 2',3'-Cyclic NADP disodium Activator / Unkown
HY-153101 Gal-G2-CNP / Unkown
HY-N12612 CNP0296775 Inhibitor / Unkown
HY-P1556 Vasonatrin Peptide (VNP) / Unkown
HY-RS02910 CNP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17182 Cnp Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23633 Cnp Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W330621 2-Chloro-4-nitrophenyl-α-D-glucopyranoside / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnp NCBI NCBI:1267