2. Gene
  3. Cbr1 - carbonyl reductase 1 Gene

Cbr1 - carbonyl reductase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CR; Cbr; PG-9-KR

Gene ID: 12408 | Gene type: protein coding

About Cbr1

Summary

Predicted to enable carbonyl reductase (NADPH) activity and oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor. Predicted to be involved in several processes, including phylloquinone catabolic process; prostaglandin catabolic process; and response to progesterone. Part of subapical complex. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human CBR1 (carbonyl reductase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cbr1 Products(1)

mRNA Protein Name
NM_007620.2 NP_031646.2 carbonyl reductase [NADPH] 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IDA
IDA: Inferred from direct assay
28878267 MGI
Biological Process GO Annotation Evidence Reference Source
involved in glucocorticoid metabolic process IDA
IDA: Inferred from direct assay
28878267 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carbonyl reductase [NADPH] 1

15-hydroxyprostaglandin dehydrogenase

20-beta-hydroxysteroid dehydrogenase

Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1)

NADPH-dependent carbonyl reductase 1

alcohol dehydrogenase [NAD(P)+] CBR1

prostaglandin 9-ketoreductase

pr

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0148 Rutin 98.09% Unkown
Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13930 Miquelianin 99.70% Unkown
HY-N2609 7,4'-Dihydroxyflavone Inhibitor 99.68% Unkown
HY-156694 Hydroxy-PP-Me 99.92% Unkown
HY-155587 Hydroxy-PP Inhibitor 99.66% Unkown
HY-121710 MonoHER 97.02% Unkown
HY-157444 5,3',4',3'',4'',5''-6-O-Ethyl-EGCG Inhibitor / Unkown
HY-157445 CBR1-IN-3 / Unkown
HY-157447 CBR1-IN-4 / Unkown
HY-157448 CBR1-IN-6 Inducer / Unkown
HY-157449 CBR1-IN-5 / Unkown
HY-157450 YF-Mo1 Inhibitor / Unkown
HY-157451 CBR1-IN-7 / Unkown
HY-157452 (8S)-Methyl zearalenone Inhibitor / Unkown
HY-RS02004 CBR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18341 Cbr1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24820 Cbr1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbr1 NCBI NCBI:873