2. Gene
  3. Capza2 - capping actin protein of muscle Z-line subunit alpha 2 Gene

Capza2 - capping actin protein of muscle Z-line subunit alpha 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cappa2; 1110053K06Rik

Gene ID: 12343 | Gene type: protein coding

About Capza2

Summary

Predicted to enable actin filament binding activity. Predicted to be involved in actin Cytoskeleton organization and barbed-end actin filament capping. Predicted to act upstream of or within actin filament capping. Located in brush border; cortical cytoskeleton; and membrane. Part of F-actin capping protein complex. Is expressed in nervous system; submandibular gland primordium; thymus primordium; and vibrissa. Orthologous to human CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Capza2 Products(1)

mRNA Protein Name
NM_007604.3 NP_031630.1 F-actin-capping protein subunit alpha-2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15850461 MGI
Cellular Component GO Annotation Evidence Reference Source
part of F-actin capping protein complex IPI
IPI: Inferred from physical interaction
19806181 MGI
located in brush border IDA
IDA: Inferred from direct assay
22114352 MGI
located in cortical cytoskeleton IDA
IDA: Inferred from direct assay
18723693 MGI
located in membrane IDA
IDA: Inferred from direct assay
18723693 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-actin-capping protein subunit alpha-2

capZ alpha-2

capping protein (actin filament) muscle Z-line, alpha 2

capping protein alpha 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01903 CAPZA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20532 Capza2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27041 Capza2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Capza2 NCBI NCBI:830