Btg2 - BTG anti-proliferation factor 2 Gene

Mus musculus

Also known as Pc3; APRO1; TIS21

Gene ID: 12227 | Gene type: protein coding

About Btg2

Summary

Predicted to enable transcription corepressor activity. Acts upstream of or within several processes, including associative learning; central nervous system development; and skeletal muscle cell differentiation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human BTG2 (BTG anti-proliferation factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Btg2 Products(1)

mRNA	Protein	Name
NM_007570.2	NP_031596.1	protein BTG2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	8663146	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within anterior/posterior pattern specification	IMP IMP: Inferred from mutant phenotype	15542835	MGI
acts upstream of or within associative learning	IMP IMP: Inferred from mutant phenotype	20020054	MGI
acts upstream of or within central nervous system neuron development	IMP IMP: Inferred from mutant phenotype	20020054	MGI
acts upstream of or within dentate gyrus development	IMP IMP: Inferred from mutant phenotype	20020054	MGI
acts upstream of or within negative regulation of neuroblast proliferation	IMP IMP: Inferred from mutant phenotype	20020054	MGI
acts upstream of neural precursor cell proliferation	IMP IMP: Inferred from mutant phenotype	20020054	MGI
acts upstream of neuroblast proliferation	IMP IMP: Inferred from mutant phenotype	20020054	MGI
acts upstream of or within protein methylation	IDA IDA: Inferred from direct assay	8663146	MGI
acts upstream of or within skeletal muscle cell differentiation	IMP IMP: Inferred from mutant phenotype	22147266	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protein BTG2

B cell translocation gene 2, anti-proliferative	BTG family member 2
NGF-inducible protein TIS21

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01663	BTG2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20698	Btg2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Btg2	NCBI	NCBI:7832

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