2. Gene
  3. Bnip3 - BCL2/adenovirus E1B interacting protein 3 Gene

Bnip3 - BCL2/adenovirus E1B interacting protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Nip3

Gene ID: 12176 | Gene type: protein coding

About Bnip3

Summary

Enables identical protein binding activity. Involved in several processes, including negative regulation of Reactive Oxygen Species metabolic process; regulation of aerobic respiration; and regulation of mitochondrion organization. Acts upstream of or within several processes, including brown fat cell differentiation; intrinsic apoptotic signaling pathway; and toxin transport. Located in mitochondrial membrane and postsynaptic density. Is expressed in several structures, including central nervous system; embryo mesenchyme; gut; musculoskeletal system; and nasal epithelium. Orthologous to human BNIP3 (BCL2 interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Bnip3 Products(1)

mRNA Protein Name
NM_009760.4 NP_033890.1 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
22044588 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within brown fat cell differentiation IDA
IDA: Inferred from direct assay
18492766 MGI
acts upstream of or within intrinsic apoptotic signaling pathway IGI
IGI: Inferred from genetic interaction
16954213 MGI
acts upstream of or within intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
16954213 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
10891486 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3

BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3

BCL2/adenovirus E1B interacting protein 1, NIP3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-121859 RU28362 Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bnip3 NCBI NCBI:664