2. Gene
  3. Bmp15 - bone morphogenetic protein 15 Gene

Bmp15 - bone morphogenetic protein 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Bmp-15; GDF-9B

Gene ID: 12155 | Gene type: protein coding

About Bmp15

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, Growth Differentiation Factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Female mice lacking a functional copy of this gene exhibit impaired fertility. [provided by RefSeq, Aug 2016]

Bmp15 Products(1)

mRNA Protein Name
NM_009757.5 NP_033887.1 bone morphogenetic protein 15 preproprotein
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19480014 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bone morphogenetic protein 15

growth/differentiation factor 9B

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01535 BMP15 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19176 Bmp15 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25665 Bmp15 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bmp15 NCBI NCBI:9210