2. Gene
  3. Bmp1 - bone morphogenetic protein 1 Gene

Bmp1 - bone morphogenetic protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pcp; Tld

Gene ID: 12153 | Gene type: protein coding

About Bmp1

Summary

This gene encodes a metalloproteinase that plays an essential role in the formation of the extracellular matrix and is also able to induce ectopic bone formation. Unlike Other bone morphogenetic proteins, the protein encoded by this gene is not closely related to transforming growth factor-beta. This protein plays in role several developmental processes. In humans, mutations in this gene are associated with osteogenesis imperfecta and with increased bone mineral density and multiple recurrent fractures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Bmp1 Products(2)

mRNA Protein Name
NM_001360021.1 NP_001346950.1 bone morphogenetic protein 1 precursor
NM_009755.3 NP_033885.2 bone morphogenetic protein 1 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables metalloendopeptidase activity IDA
IDA: Inferred from direct assay
19079247 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19079247 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bone morphogenetic protein 1

mammalian tolloid protein

procollagen C-proteinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13102 UK-383367 Inhibitor 99.92% Unkown
HY-RS01533 BMP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-201672 18:1 BMP (S,R) ammonium / Unkown
HY-N15998 18:1 BMP (R,R) ammonium / Unkown
HY-N16017 18:1 BDP (S,S) ammonium / Unkown
HY-RS18338 Bmp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24817 Bmp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bmp1 NCBI NCBI:649