Slc7a2 - solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Gene

Mus musculus

Also known as Tea; 20.5; Cat2; Atrc2; CAT-2

Gene ID: 11988 | Gene type: protein coding

About Slc7a2

Summary

Enables L-amino acid transmembrane transporter activity. Involved in regulation of macrophage activation. Acts upstream of or within several processes, including L-alpha-amino acid transmembrane transport; nitric oxide biosynthetic process; and nitric oxide production involved in inflammatory response. Is integral component of membrane. Is expressed in several structures, including alimentary system; bone; brain; genitourinary system; and respiratory system. Orthologous to human SLC7A2 (solute carrier family 7 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc7a2 Products(2)

mRNA	Protein	Name
NM_001044740.2	NP_001038205.1	cationic amino acid transporter 2 isoform 2
NM_007514.3	NP_031540.2	cationic amino acid transporter 2 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables L-arginine transmembrane transporter activity	IDA IDA: Inferred from direct assay	9174363	MGI
enables L-arginine transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	11278602	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in L-arginine transmembrane transport	IDA IDA: Inferred from direct assay	9174363	MGI
acts upstream of or within L-arginine transmembrane transport	IMP IMP: Inferred from mutant phenotype	11278602	MGI
acts upstream of or within establishment of localization in cell	IMP IMP: Inferred from mutant phenotype	11278602	MGI
acts upstream of or within macrophage activation	IMP IMP: Inferred from mutant phenotype	16703566	MGI
acts upstream of or within nitric oxide biosynthetic process	IMP IMP: Inferred from mutant phenotype	12675924	MGI
acts upstream of or within nitric oxide production involved in inflammatory response	IMP IMP: Inferred from mutant phenotype	11278602	MGI
acts upstream of or within regulation of inflammatory response	IMP IMP: Inferred from mutant phenotype	17003120	MGI
involved in regulation of macrophage activation	IMP IMP: Inferred from mutant phenotype	16670299	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in membrane	IDA IDA: Inferred from direct assay	8187816	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cationic amino acid transporter 2

T-cell early activation protein	amino acid transporter, cationic 2 (low affinity)
cationic amino acid transporter 2A	cationic amino acid transporter 2B
low affinity cationic amino acid transporter 2	solute carrier family 7 member 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS21940	Slc7a2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13328	SLC7A2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc7a2	NCBI	NCBI:6542

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