Atp5b - ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit Gene

Mus musculus

Also known as Atp5f1b

Gene ID: 11947 | Gene type: protein coding

About Atp5b

Summary

Predicted to enable several functions, including adenyl ribonucleotide binding activity; angiostatin binding activity; and proton-transporting ATPase activity, rotational mechanism. Predicted to contribute to ATP hydrolysis activity and proton-transporting ATP Synthase activity, rotational mechanism. Acts upstream of or within cellular response to interleukin-7; lipid metabolic process; and negative regulation of cell adhesion involved in substrate-bound cell migration. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; eye; heart; and integumental system. Orthologous to human ATP5F1B (ATP Synthase F1 subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Atp5b Products(1)

mRNA	Protein	Name
NM_016774.3	NP_058054.2	ATP synthase subunit beta, mitochondrial precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19941651	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular response to interleukin-7	IDA IDA: Inferred from direct assay	29581031	MGI
acts upstream of or within lipid metabolic process	IMP IMP: Inferred from mutant phenotype	17612527	MGI
acts upstream of or within negative regulation of cell adhesion involved in substrate-bound cell migration	IMP IMP: Inferred from mutant phenotype	17612527	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrion	IDA IDA: Inferred from direct assay	19808025	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ATP synthase subunit beta, mitochondrial

ATP synthase F1 subunit beta	ATP synthase, H+ transporting mitochondrial F1 complex, alpha subunit
mitochondrial ATP synthase, H+ transporting F1 complex beta subunit

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-139185	PROTAC ERRα Degrader-3	Inhibitor	98.82%	Unkown

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