1. Gene
  2. Apod - apolipoprotein D Gene

Apod - apolipoprotein D Gene

Mus musculus
Gene ID: 11815 | Gene type: protein coding

About Apod

Summary

The protein encoded by this gene is a component of high-density lipoprotein (HDL), but is unique in that it shares greater structural similarity to lipocalin than to Other members of the Apolipoprotein family, and has a wider tissue expression pattern. The encoded protein is involved in lipid metabolism, and ablation of this gene results in defects in triglyceride metabolism. Elevated levels of this gene product have been observed in multiple tissues of Niemann-Pick disease mouse models, as well as in some tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Apod Products(3)

mRNA Protein Name
NM_001301353.1 NP_001288282.1 apolipoprotein D precursor
NM_001301354.1 NP_001288283.1 apolipoprotein D precursor
NM_007470.4 NP_031496.2 apolipoprotein D precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of lipoprotein lipid oxidation IMP
IMP: Inferred from mutant phenotype
18419796 MGI
involved in response to reactive oxygen species IMP
IMP: Inferred from mutant phenotype
18419796 MGI
Cellular Component GO Annotation Evidence Reference Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
11744388 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

apolipoprotein D

Orthologs Information

Species Symbol Source ID
Homo sapiens Apod NCBI NCBI:347