2. Gene
  3. Tbp - TATA box binding protein Gene

Tbp - TATA box binding protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as TFIID

Gene ID: 117526 | Gene type: protein coding

About Tbp

Summary

Enables DNA binding activity. Contributes to RNA polymerase II general transcription initiation factor activity. Involved in positive regulation of transcription, DNA-templated and spermatogenesis. Located in nucleus. Part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in late onset Parkinson's disease; schizophrenia; spinocerebellar ataxia type 17; and type 1 diabetes mellitus. Orthologous to human TBP (TATA-box binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Tbp Products(1)

mRNA Protein Name
NM_001004198.1 NP_001004198.1 TATA-box-binding protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
16112330 RGD
contributes to RNA polymerase II general transcription initiation factor activity IDA
IDA: Inferred from direct assay
7980586 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10471789 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
7980586 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
8776734 RGD
Cellular Component GO Annotation Evidence Reference Source
part of transcription factor TFIID complex IDA
IDA: Inferred from direct assay
7980586 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TATA-box-binding protein

Related Agents

Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-16579A Etifoxine Activator 99.96% Phase 3
HY-16579 Etifoxine hydrochloride Activator 99.87% Phase 3
HY-105056 Bretazenil Agonist 99.13% Phase 3
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-172940 TBP-134 Inducer / Unkown
HY-RS14266 TBP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18225 Tbp Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24702 Tbp Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tbp NCBI NCBI:6908
Macaca fascicularis Tbp NCBI NCBI:101866697
Mus musculus Tbp NCBI NCBI:21374